---

Economy and safety are two important components in structural design process and stablishing a balance between them indeed results in improved structural performance specially in large-scale structures including space lattice domes. Topology optimization of geometrically nonlinear single-layer lamella, network, and geodesic lattice domes is implemented using enhanced colliding-bodies optimization algorithm for three different spans and two different dead loading conditions. Collapse reliability index of these optimal designs is evaluated to assess the safety of the structures against overall collapse using Monte-Carlo simulation method. The numerical results of this study indicate that the reliability index of most of the optimally designed nonlinear lattice domes is low and this means that the safety of these structures against overall collapse is questionable.